KMID : 0387820140210020157
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Clinical Pediatric Hematology-Oncology 2014 Volume.21 No. 2 p.157 ~ p.162
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An Adolescent Case of Castleman Disease of the Plasma Cell Type Treated with Radiotherapy
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Heo Tea-Hoon
Lim Hyun-Wook Sim Ji-Hyun Lee Jung-Hwa Lee Eun-Hee Lee Kwang-Chul
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Abstract
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Castleman disease (CD) is a disorder with distinct lymphoid hyperplasia of unknown origin, and it is rare in children. There are two major forms of CD: unicentric (localized) and multicentric. Pathologically, it can be categorized into three subtypes: hya-line-vascular, plasma cell, and mixed types. We experienced a 15-year-old boy with his-topathologically proven mediastinal CD of the plasma cell type. He was referred to our hospital because of mediastinal widening in a chest x-ray found by chance. Surgery was performed to resect two right paratracheal masses and subtotal excision was done. As complete surgical resection was not possible, the patient subsequently received three-di-mensional conformal radiation therapy (total 5,400 cGy in 27 fractions). The size of the mass decreased, and his clinical symptoms regressed without any side effects from radiotherapy. Here we report a case of unicentric plasma cell type CD, treated with ra-diotherapy due to incomplete surgical resection.
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KEYWORD
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Castleman disease, Child, Lymphoproliferative disorders, Radiotherapy, Case reports
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